Cistanche deserticola decoction alleviates the testicular toxicity induced by hydroxyurea in male mice

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Cistanche deserticola decoction alleviates the testicular toxicity induced by hydroxyurea in male mice.

This study aimed to evaluate testicular toxicity induced by hydroxyurea (HU) and the possible counteracting effect of an aqueous extract of Cistanche deserticola (CD). HU is an antineoplastic drug that has potential reproductive toxicity, and Herba Cistanche has been used as a tonic for the reproductive system for thousands of years. Sixty mice were randomly divided into five groups. Except mic...

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Saussurea Costus Extract Has Anti-inflammatory, Antioxidant, and Hormonal Effects Against Testicular Toxicity Induced by Oxaliplatin in Male Albino Rats

Background: Testicular dysfunction is one of the common side effects that results from the treatment with oxaliplatin® as a chemotherapy drug, and pharmaceutical search for agents to relieve the side effects are underway. The current study explored the possible ameliorative and regenerative effects of Costus ethanolic extract against testicular degeneration in male rats induced by oxaliplatin. ...

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ژورنال

عنوان ژورنال: Asian Journal of Andrology

سال: 2013

ISSN: 1008-682X,1745-7262

DOI: 10.1038/aja.2013.73